Bronnen, noten en/of referenties
- ↑ Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF (Feb 1998). A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci U S A 95 (2): 588–93. PMID 9435236. PMC 18464.
- ↑ Medzhitov R, Preston-Hurlburt P, Janeway CA Jr (Aug 1997). A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 (6640): 394–7. PMID 9237759. DOI: 10.1038/41131.
- ↑ Entrez Gene: TLR4 toll-like receptor 4. Gearchiveerd op 7 maart 2010.
- ↑ Zhang, Guolong, Ghosh Sankar (Mar. 2002). Negative regulation of toll-like receptor-mediated signaling by Tollip. J. Biol. Chem. 277 (9): 7059–65 (United States). ISSN: 0021-9258. PMID 11751856. DOI: 10.1074/jbc.M109537200.
- ↑ Chuang, Tsung-Hsien, Ulevitch Richard J (May. 2004). Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors. Nat. Immunol. 5 (5): 495–502 (United States). ISSN: 1529-2908. PMID 15107846. DOI: 10.1038/ni1066.
- ↑ Doyle, Sean E, O'Connell Ryan, Vaidya Sagar A, Chow Edward K, Yee Kathleen, Cheng Genhong (Apr. 2003). Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4. J. Immunol. 170 (7): 3565–71 (United States). ISSN: 0022-1767. PMID 12646618.
- ↑ Rhee, S H, Hwang D (Nov. 2000). Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase. J. Biol. Chem. 275 (44): 34035–40 (UNITED STATES). ISSN: 0021-9258. PMID 10952994. DOI: 10.1074/jbc.M007386200.
- ↑ Fitzgerald, K A, Palsson-McDermott E M, Bowie A G, Jefferies C A, Mansell A S, Brady G, Brint E, Dunne A, Gray P, Harte M T, McMurray D, Smith D E, Sims J E, Bird T A, O'Neill L A (Sep. 2001). Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413 (6851): 78–83 (England). ISSN: 0028-0836. PMID 11544529. DOI: 10.1038/35092578.
- ↑ Re, Fabio, Strominger Jack L (Jun. 2002). Monomeric recombinant MD-2 binds toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness. J. Biol. Chem. 277 (26): 23427–32 (United States). ISSN: 0021-9258. PMID 11976338. DOI: 10.1074/jbc.M202554200.
- ↑ Shimazu, R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K, Kimoto M (Jun. 1999). MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189 (11): 1777–82 (UNITED STATES). ISSN: 0022-1007. PMID 10359581.
- ↑ Tidswell, M, Tillis, W, Larosa, SP, Lynn, M, Wittek, AE (2010). Phase 2 trial of eritoran tetrasodium (E5564), a Toll-like receptor 4 antagonist, in patients with severe sepsis. Critical care medicine 38 (1): 72–83. PMID 19661804. DOI: 10.1097/CCM.0b013e3181b07b78.
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