De Borhyaenoidea omvat drie families en enkele basale taxa. De verwantschap binnen de Borhyaenoidea wordt in onderstaand vereenvoudigd cladogram[2] weergegeven:
↑The evolution of the Cenozoic terrestrial mammalian predator guild in South America: competition or replacement? FJ Prevosti, A Forasiepi & N Zimicz. Journal of Mammalian Evolution (2013).
↑Insights into the Neotropics prior to the Great American Biotic Interchange: new evidence of mammalian predators from the Miocene of Northern Colombia. C Suarez et al. Journal of Vertebrate Paleontology (2015).